Effective Cell Disruption with Bullet Blender
Cell disruption involves breaking cells open to release its components, such as DNA, RNA, protein, organelles, or other particles of interest. When lysing different cell samples, it is ideal to recover the highest viable yield of these intracellular molecules. The Bullet Blender cell disruptor uses lysis beads to homogenize cells to obtain a wide range of intracellular components while also maximizing the yield.Â
The Bullet Blender cell disruptor prepares up to 24 samples in just minutes. It uses patented striking technology to thoroughly lyse cell and tissue samples for downstream applications. All of the samples are automatically homogenized in the same manner, with high yields, so there is very little variation from sample to sample. See the protocols page for preparation times and speeds.
Results Using the Bullet Blender Cell Disruptor
DNA From Plant and Small Organism Samples Extracted Using the Next Advance Bullet Blender and DNAmite Plant Kit by Microzone. DNA from 30mg of strawberry and rose leaves and DNA from 50 mg of small organism samples was extracted and run on a 1% Agarose gel. M – 1 kb ladder.
RNA from Mouse Liver Samples Extracted Using Next Advance Bullet Blender and RNA Extraction Kit by Microzone. RNA from 50 mg of mouse liver was homogenized using the Bullet Blender Storm Pro. RNA was extracted from the homogenate.
No Cross Contamination
No part of the Bullet Blender cell disruptor ever touches the cells – the sample tubes are kept closed during homogenization. There are no probes to clean between samples.
Samples Stay Cool
The Bullet Blenders’ innovative and elegant design provides convective cooling of the cell and tissue samples, so they do not heat up more than several degrees. In fact, our Gold+ models hold the sample temperature at around 4ºC.
Easy and Convenient to Use
Just place beads and buffer along with your cells in standard tubes, load tubes directly in the Bullet Blender, select time and speed, and press start.
