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News - Next Advance molecular biology laboratory instruments and equipment

02.09.2012 See us at virtual BioConference Live

Come visit the Next Advance booth on February 15 and 16 at www.BioConferenceLive.com . . .
. . . read more . . .

Next Advance, Inc.
1548 Burden Lake Road
Averill Park, NY 12018, USA

Phone: 1.518.674.3510
in USA 1.800.738.1681
Fax: 1.518.674.0189 info@nextadvance.com

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The easiest and coolest way to lyse cells and homogenize tissue.

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  • "It's a very useful device for making tissue lysates. We no longer use sonication for DNA, RNA and protein preparation from multiple tissue samples."

    Prof. Michael Sherman, Boston University School of Medicine

     

  • "The Bullet Blender has made our clinical lab much more efficient; we get consistent results in less time. We cannot imagine going back to hand vortexing for our whole blood extractions."

    Kimberly Dumont, supervisor, Dartmouth Reference Lab

     

  • "I can count on it for fast consistent results."

    Dr. Denis Schewe, Mt. Sinai Medical Center, New York City

     

  • "What I've found is that the instrument works very well, is faster than the Bead Beater, accommodates more samples and is considerably quieter... [I] get consistently uniform cell breakage."

    Dr. Joseph Geisberg, Harvard Medical School

     

  • "This past January [2008] we purchased a Bullet Blender from Next Advance. ... Let me begin by saying that we are extremely satisfied with the product! We have been able to implement it into a number of protocols that we use in our lab. Other labs in our department have also taken a liking to the unit and have been using it along side our lab."

    Dr. Kyle Bender, Queen's University, Kingston, Ontario, CANADA

     

  • "The Bullet Blender® lets us reduce variability and user error and increase productivity."

    Dr. Scott Gridley, Director of Protein Sciences, Blue Sky Biotech, Inc., Worcester, MA

     

  • "Using the Dounce homogenizer, I can process eight tumors in an hour and a half. With the Bullet Blender, I can homogenize twenty in fifteen minutes."

    Dr. Alejandro Adam, Albany Medical Center, New York

     

  • "Our extraction staff have loved the Bullet Blenders, they have really helped with the workflow!" ... "They do a great job homogenizing for us, and save our techs from repetititve motion injuries, and help with time management. We love them!"

    Chantry Clark, CDAT Lead Technologist, ARUP Labs, Utah

     

  • "I love it!! ... I'm going to try and get another one."

    Shari Kohut, MLT ASCP, Women and Children's Hospital of Buffalo

     

  • "We used to use a mortar and pestle grinder and it took hours and hours and hours to homogenize our samples. The Bullet Blender has increased our throughput tremendously."

    Dr. Christopher Ward, University of Maryland

     

  • "The Bullet Blender homogenizes our samples so well, our protein yield is almost too good."

    Dr. Donna Newman, North Carolina State University

     

  • "It does work great for westerns ... It's a lot faster."

    Dr. Timothy Bartness, Georgia State University

     

  • "That machine is a lifesaver! ... It worked out so well, we're contemplating purchasing a second one."

    Dr. Lou Casta, Fraunhofer USA

     

  • "...the results are great! ... We have run it on the Agilent chip and the RNA integrity numbers (RIN) are 10 and 8.6 for both of the samples."

    Phuong Nguyen, Translational Genomics Group, Baylor Health

     

  • "We use the Bullet Blender to disrupt mycobacteria and different types of gram-negative bacteria for a variety of applications and are very happy with the results we get."

    Martin Pavelka, Ph.D., University of Rochester, School of Medicine and Dentistry

     

  • "I love the Bullet Blender! We work on the mouse model for chlaymdia and often have to remove the uteri from the mice and homogenize by hand. I used it the other day and was amazed how well it homogenized the tissue. We can do 24 samples in just 5 minutes-amazing. What used to take us hours we can do in just 5 minutes."

    Cheryl Champion, Ph.D., Pathology & Laboratory Medicine, UCLA

     
 

 

The BULLET BLENDER® enables you to homogenize, disrupt, or lyse up to 24 tissue or cell culture samples at a time. Load the samples into standard polypropylene tubes, then place them in the BULLET BLENDER. The "bullets" in the instrument vigorously strike all of the tubes and homogenize your sample in minutes. The Bullet Blender is available with Air Cooling™ to preserve your sample quality!

tissue homogenizer and cell disrupter organ homogenization lysis extraction

Applications:

Homogenize Tissue
Liver, Spleen, Kidney, Brain, Adipose, Bladder, Eye, Thyroid, Gallbladder, Muscle, Pancreas, Testes, Meconium, Thymus
Homogenize Tougher Tissue
Heart, Aorta, Tumor, Tail Snips, Colon, Lung, Blood Vessel, Trachea, Cartilage, Epithelium, Stomach, Intestine, Larynx, Mouse Femur, Pharynx, Umbilical Cord, Skin, Uterus
Lyse Cells
E. coli, Mamallian cell culture, Yeast
Homogenize Plant Material
Leaves, Beans, Nuts, Roots
Homogenize Small Organisms
Zebrafish, Drosophila
Whole Cell Isolation
Bacteria, Lymphocytes, Blood Cells
Organelle Isolation
Nucleus, Mitochondria

See some publications referencing the Bullet Blender for these applications.

DNA

RNA

Protein
From plant samples
homogenizer plant samples DNA		 From tail snips
homogenized snail tips using Bullet Blender		 From E. Coli samples protein from homogenized E. coli

Genomic DNA samples in agarose gel stained with ethidium bromide


Lanes 1-4 = Tobacco leaf DNA
lambda = lambda phage Hind II digest
Lanes 5-8=Rice leaf DNA samples

 Total RNA gel. RNA Integrity Number = 8.5
(thanks to Madhu Prasad @ U. Michigan)		 SDS-PAGE gel stained with Coomassie Blue

wc = whole cell
sf = soluble fraction
Left two lanes control Right two lanes induced
 

The Bullet Blender® Family

The Bullet Blender Storm tissue homogenizer cell disruption New!! BBY24M- Bullet Blender® STORM
Our most powerful model!
  • Perfect for tough samples such as mouse femur, tumor and skin
  • Faster homogenization
  • Up to 24 samples in snap cap microcentrifuge tubes
  • Air cooling
  • Available with CE certification

BBY24M Bullet Blender Storm...................................... more info
BBY24M-CE with CE certification................................. more info
BBX24- Bullet Blender®
Our original Bullet Blender can homogenize up to 24 samples in microcentrifuge tubes. Ideal for samples up to 300mg. Also available with air cooling (blue models) and CE certification.

BBX24 Bullet Blender........................ more info
BBX24-CE with CE certification......... more info
BBX24B Bullet Blender Blue............. more info
BBX24B-CE with CE certification....... more info
BBX24W-Bullet Blender® for
Screw-Cap Tubes
The Screw-Cap Bullet Blender can homogenize up to 24 samples in screw-cap microcentrifuge tubes. Ideal for samples up to 300mg. Also available with air cooling (blue models) and CE certification.

BBX24W Bullet Blender for
Screw Cap Tubes................................. more info
BBX24W-CE with CE certification......... more info
BBX24BW Bullet Blender Blue for
Screw Cap Tubes.................................. more info
BBX24BW-CE with CE certification....... more info
BBX5MB- Bullet Blender® Blue 5
The Bullet Blender 5 can homogenize up to 12 samples in 5ml screw-cap tubes. Ideal for samples up to 1g. Air cooling included. CE certification available.

BBX5MB Bullet Blender Blue 5......... more info
BBX5MB-CE with CE certification..... more info
BB50-DX- Bullet Blender® 50 DX
The Bullet Blender 50 DX can homogenize up to 4 tough tissue samples or up to 8 soft samples in 50 mL tubes in parallel. Each tissue sample up to 3.5 g or cell culture combined with buffer up to 20 ml. Air cooling included.

BB50-DX Bullet Blender 50 DX......... more info
BB50-DX-CE with CE certification..... more info

Need help selecting a model?  Check out our Bullet Blender Selection Guide


Bullet Blender® Models for Special Applications
field model tissue homogenization and cell disrupter

The BULLET BLENDER® FIELD MODEL Enhancement

A fully portable, lightweight unit that will allow you to homogenize samples as you collect them. The Field Model contains an internal rechargeable battery, capable of 25 complete 5-minute runs of 6 tubes each between charging. Only available for domestic sales. Equipped with a padded handle for ease of carrying. This factory upgrade is available on models that use microcentrifuge tubes. This is a factory installed upgrade. . . . more info
Bullet Blender Homogenizer in BioBox Containment Unit

The BIOBOX™ BULLET BLENDER®

With this factory enhancement, the Bullet Blender is built into a locking containment unit. The housing and containment unit are clear so leaks or spills are readily identifiable. The pressure in the secondary container is decreased so that a break in the seal would lead to leakage inward, not outward. The controls for this integrated system are mounted on the outside of the containment unit. Available for microcentrifuge screw cap tube Bullet Blender models: BBX24W and BBX24BW. This is a factory installed enhancement and requires purchase of the Bullet Blender at the time of purchase of the BioBox. . . .more info
 

Consistent and High Yield Results

The BULLET BLENDER prepares up to 24 samples in just minutes. All of the samples are automatically homogenized in the same manner, with high yields, so there is very little variation from sample to sample. See the Protocols pages for preparation times and speeds.

No Cross-Contamination or Sample Loss

There are no probes or blades to cause cross contamination or sample loss, which also means there are no parts to clean between runs. The sample tubes are kept closed and self-contained during homogenization.

Samples Stay COOL

No cool down required. The instrument uses very little power due to the unique, patented design, so there is very little heat build up in the instrument or inside the sample tubes. It uses a small DC motor to agitate the individual tubes. Also, because the motor does not need to agitate any heavy platforms or plates, it is small and will last for years.

Easiest To Use

Simply place your sample, beads and buffer in standard tubes, and load the tubes into the BULLET BLENDER. Tune the extent of disruption by adjusting the run time and speed. Afterwards, place the sample tubes in a centrifuge to separate the lysate. No special holders are needed. There are no clamp plates nor locking rings to fiddle with.

Risk Free Purchase

BULLET BLENDER units come with a 30 day money back guarantee and a 2 year warranty. The simple, reliable design enables the BULLET BLENDER to sell for one half to one fifth the price of ultrasonic or other agitation based instruments, yet provides an easier, quicker, cooler technique.

4 year extended warranty available.
For more information, click here.
 

Air Cooling™ in The Bullet Blender®:

The Air Cooling™ system draws air into the Bullet Blender, keeping your samples at ambient temperature. This feature is particularly effective if your samples are sensitive to heat and you are using your Bullet Blender in a refrigerator or a cold room. The Air Cooling™ is also useful for preventing the inside of your Bullet Blender unit from heating up if you are running several consecutive homogenization cycles. Air Cooling™ is an option on the microtube models and standard on the 5 mL and the 50 mL tube models.

 

 

purchase Bullet Blender homogenizer / disrupter tissue / cells

 

Need help selecting a model?  Check out our Bullet Blender Selection Guide

BULLET BLENDER® models

 

BBX24

BBY24M

BBX24W

BBX5MB

BB50-DX
Number of Samples
24 Tubes
24 Tubes
24 Tubes
12 Tubes
8 Tubes
Tubes
1.5 to 2.0mL* snap-top polypropylene microcentrifuge tubes (e.g. Eppendorf® Safe-Lock™)
1.5 mL Eppendorf® Safe-Lock™ tubes
1.5ml screw-top polypropylene microcentrifuge tubes (e.g. Axygen, Corning®)
5mL screw-cap
50mL polypropylene skirted screw-cap tubes, placed in sleeves
Maximum Fill Volume
1.2mL, or 1.5mL
1.2mL
1.2mL
3ml
20mL
Maximum Tissue Sample Size
300 mg
1 g
3.5 g
With Air Cooling™?
Included
Included
Included
CE Certified option?
 Yes
Integrated BioBox™ Enclosure?
Not available
Not available
Not available
Not available
Field Model
Not available
Not available
Not available

 *When using 2ml tubes, we recommend using a minimum of 2 tubes per homogenization cycle.

The Bullet Blender® uses 24V DC supplied by a small external power supply that plugs into a wall outlet. Next Advance will provide the appropriate power supply for your region.

Features:

  • Compact - The footprint is only 9in. (22cm) wide by 11in. (28cm) deep. The BB50-DX model is 13 in. (33 cm) wide by 14in. (35cm) deep.
  • High Throughput
  • User friendly with only two settings to select: time and speed (intensity)
  • The time of the run may be adjusted from 1-5 minutes (15 minutes for the Bullet Blender Blue 50). The Bullet Blender will automatically stop after the selected time is up.
  • The Bullet Blender® has 10 speeds, easily selectable from a front-panel control. This wide array of speeds allows the Bullet Blender® to be used for gentle vortexing, vigorous homogenization, or anything in between.
  • Versatile -The Bullet Blender® can be used in temperatures ranging from 4°C to 60°C (avoid condensation, which will damage electronics and void the warranty).
  • Requires only an electrical outlet for operation.
  • CE certified 24V power supply, shipped with the proper plug configuration for your wall outlets.
  • CE certified instruments with upgraded electronics available.
  • Air Cooling™ on "BLUE" models prevents samples from heating up when processing multiple rounds. The COOLEST homogenizer available!
  • 30 day money back guarantee
  • 2 year warranty
  • Made in the USA

Field Blender Enhancement

  • Battery provides over 2 hours of continuous use.
  • Padded handle for easy transport.
  • Modified capacity for 6 microcentrifuge tubes to maintain performance when battery is low.
  • Car power adapter included.

BioBox™ Bullet Blender®

  • Secondary enclosure for containing contaminants.
  • Negative Pressure to ensure leaks are inward and contaminants do not escape.
  • Interlocks to indicate that the secondary enclosure is closed and seal is intact.
  • Transparent - to visually confirm tube and sample integrity.
  • Bullet Blenders with the BioBox™ enhancement are final sale only.
 

 

Air Cooling | Use and Operation

Want to know more about homogenization methods in general? Click here for an overview.

 

 

Air Cooling™:

What is Air Cooling™?

The Air Cooling™ models have devices which exchange air with their surroundings; they do not have refrigeration units. Air Cooling™ effectively draws cold air into the instrument if you are using the Bullet Blender® in a cold room or a refrigerated cabinet. Air Cooling™ is also useful if you're running several sample cycles in a row or if your samples are extra sensitive to heating up. Normally, the samples in the Bullet Blender® only heat up a few degrees and stay quite cool. However, if you're running a second batch of samples soon afterward, they will heat up a little more because the Bullet Blender® is starting out slightly warmer. The Air Cooling™ keeps the Bullet Blender® cooler so that the first batch of samples heat up a little less and subsequent batches are kept just about as cool as the first batch.

Which models have Air Cooling™?

The Air Cooling™ feature comes on the "Blue" models: the Bullet Blender® Blue which uses microcentrifuge tubes, the Bullet Blender® Blue 5 which uses 5 mL tubes and the Bullet Blender® Blue 50 which uses 50 mL tubes.  Air Cooling™ is also included with the Bullet Blender® Storm.

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Use and Operation:

Before using, please see our General Guidelines for Use

What types of tubes can be used?

The Bullet Blender® Storm works with 1.5ml Eppendorf® Safe-Lock tubes. The Bullet Blender® and Bullet Blender® Blue work with 1.5 mL, 1.7 mL, and 2.0 mL polypropylene sample tubes, including conical and round bottom microcentrifuge snap-cap tubes. We recommend Eppendorf® Safe-Lock tubes.  When using 2ml tubes in the the Bullet Blender® or the Bullet Blender® Blue we recommend using a minimum of 2 tubes per homogenization cycle.  The screw cap models use Axygen® and Corning® 1.5 ml screw cap tubes. The Bullet Blender® Blue 5 units work with 5ml Axygen® brand screw top transport tubes. The Bullet Blender 50-DX units work with 50 mL skirted (self-standing) polypropylene tubes, such as Axygen® brand or Corning® brand. The slightly hazy polypropylene tubes are tougher and resist the striking better than the clearer tubes, which might crack at higher speeds. Use high quality tubes, rather than bargain brand tubes which are not as strong.

How do you set the Bullet Blender® to mix, disrupt, or homogenize different types of samples?

You can adjust the speed and the duration. Adjusting the speed affects how firmly the balls will strike the sample tubes, while adjusting the duration affects the total number of impacts. Homogenizing tough tissue requires longer durations at full speed, while mixing requires lower speeds.

How easy is it to operate the Bullet Blender®?

Simply place up to 24 sample tubes in the holders, set the desired duration and speed, and push start. All the samples will be processed simultaneously, without any chance of cross contamination.

How much volume of sample can be homogenized in each microcentrifuge tube?

For the BBX24 model Bullet Blenders, we recommend using 50-300mg of tissue in a standard microcentrifuge tube. Less than 50mg will work, but it requires careful attention to the amount of beads and volume of homogenization buffer. As with any experiment, errors become larger as the measured quantity gets smaller, so reproducibility becomes an issue. Samples larger than 300mg are not recommended. The air volume inside the tube is critical to allow the sample to be ground up inside the tube, so if the tube is more than 75% full, the efficiency of the homogenization is reduced. The 5 mL tubes can hold up to about 1 g of sample tissue or cultured cells, and a total of 3.5 mL of sample, buffer, and beads combined. The 50 mL tubes can hold up to about 3.5 g of sample tissue or cultured cells, and a total of 20 mL of sample, buffer, and beads combined.

Do sample tubes need to be placed symmetrically?

No. There are no restrictions as to which holes to place your sample tubes in, however you may get better results if you space them apart as evenly as possible.

How do you retrieve the sample from the tubes?

After the Bullet Blender® stops, centrifuge the tubes to clarify the lysate prior to use in your molecular biology applications.

Which beads should I use?

The protocols page contains suggested beads, speeds, and durations for processing many types of tissues and cells. The Bullet Blender®beads page has a bead selection table. The two basic rules for bead selection: (1) use denser beads for tougher samples, and (2) use beads of a comparable size to the size of your samples to maximize the effectiveness of collisions between beads and samples. For example, if you wanted to lyse bacterial cells with a soft membrane, use small glass beads. If you want to homogenize larger pieces of tough tissue, use large steel beads. You can also contact our technical support staff at techsupport@nextadvance.com if you have any questions.

I am trying to process tough samples in the Bullet Blender® and the homogenization is incomplete. How can I improve my results?

There are several ways that you can increase the homogenization of your samples.

  • Examine the shape of your samples- long thin samples will homogenize faster than cube-shaped or round samples.
  • Try cutting your samples into smaller pieces.
  • If you are running many samples at once in the Bullet Blender, try runing fewer tubes at a time. If a sample is extremely tough (e.g. mouse femur) you may only be able to achieve complete homogenization with 2-4 tubes at a time.
  • If you are using the BB50-DX make sure that all of the sleeves are removed except for the sleeves containing tubes.

 

I previously owned another bead mill homogenizer. Can I use the same protocols that we developed for the other homogenizer with the Bullet Blender®?

No, the mechanism of action is different from all other homogenizers on the market. Our patented striking technology makes the Bullet Blender both highly efficient and effective. If you use another product's protocol with the Bullet Blender, you are very likely to experience different results. Please use one of our established protocols, or empirically determine a protocol that works best for your samples.

We would like to use Fisherbrand tubes with the Bullet Blender®. Do they perform well?

Due to difference in shape, Fisherbrand tubes are more susceptible to wear in the Bullet Blender. We therefore recommend that you avoid using Fisherbrand tubes with the Bullet Blender. If you must use Fisherbrand tubes, do not use them in runs of more than four minutes.

Why is there a three tube minimum for Bullet Blender® 5 and a two tube minimum for the Bullet Blender® 50-DX?

These Bullet Blender models contain larger motors. If all the energy were directed at a single tube, the tube might break. Tubes partly filled with water can be used in place of a tube filled with sample.

Is it possible to homogenize tissue that has been frozen in liquid nitrogen?

It is possible to homogenize tissue that was frozen in liquid nitrogen. Immerse the frozen tissue in cold buffer and allow it to thaw, then treat it as you would any other sample. If the tissue was dried before it was frozen, you can pulverize the tissue by running the tissue with beads only (no buffer), then adding the cold buffer and running again to complete the homogenization. You cannot homogenize "wet" tissue while it is still frozen, as it will effectively be a block of ice and homogenization efficiency will be very poor.

Back to top

Contact us if you have any more questions.

Our experienced staff of molecular biologists have worked to provide you with a set of optimized protocols for the homogenization of various tissue, cell types, and organisms so you can spend less time troubleshooting and more time getting results.

All of our currently available protocols are listed below. Please read the General Guidelines before using the Bullet Blender® in any application.

 


Types of Samples

Protocols for BBX24 models®

Protocols for BBX5MB®

Protocols for BB50-DX®
Cell Culture
Animal Tissue
Plant Tissue
 Corn Plant
Small Organisms
Extraction of Small Cells
    
Protocols for Use with Kits
    


Adobe Acrobat Reader required to view protocols. Click Here to download Adobe PDF Reader

If you need help developing an assay with the Bullet Blender®, feel free to e-mail our tech support at support@NextAdvance.com and we'll do our best to assist you.

If you have developed a protocol with the Bullet Blender that is not listed on this page, or you have developed a protocol that works better for certain applications, please share it with everyone! E-mail it to us at support@NextAdvance.com or send it using our support form and we'll review it and add it to our list of protocols. Don't worry - we'll acknowledge you for it! Thanks!

PLEASE NOTE: The protocols used with the Bullet Blender are different than protocols used with other bead-mill homogenizers. If you previously used another product, please be sure not to use its protocols with the Bullet Blender, as you will very likely experience different results.

Does the protocol use a different kind of bead than the type you currently have? Click here for pricing and ordering.

 

BBX24 Bullet Blender homogenizer $2,495.00

BBX24-Bullet-Blender-homogenizer

This homogenizer for tissue or cell cultures, can process up to 24 samples in parallel, each sample up to 0.3g each in a microcentrifuge tube. It is very easy to load samples and uses very little power so samples do not heat up significantly. Also use it to vortex samples.

Includes the following:

  • The BULLET BLENDER® (with new improved housing!)
  • Operator's manual
  • 24V DC Wall plug power supply (UL/CE)
  • Basic starter kit which includes:
    • Bead Sample Pack BSP-MC contains 10mL each of eight different bead types.
    • Spatula for dispensing beads

Select on the pull down menus below:

  • the model for use with snap cap tubes (standard) or screw cap tubes
  • standard or upgraded electronics and CE certification ($200 additional)
  • standard 2 year warranty or extended 4 year warranty with priority repair service ($293 additional)
  • basic starter kit (included, as described above) or a deluxe starter kit (described on the accessories tab)
 

BBX24B Bullet Blender Blue homogenizer $2,945.00

BBX24B-Bullet-Blender-Blue-homogenizer

The BULLET BLENDER® BLUE improves upon the original Bullet Blender® the BLUE model has Air Cooling technology. It keeps the samples from heating up when processing multiple rounds of samples. This unit is also for homogenizing, mixing or vortexing in microcentrifuge tubes (1.5 to 2.0 mL), up to 24 at a time.

Includes the following:

  • The BULLET BLENDER® (with new improved housing!)
  • Operator's manual
  • 24V DC Wall plug power supply (UL/CE)
  • Basic starter kit which includes:
    • Bead Sample Pack BSP-MC contains 10mL each of eight different bead types.
    • Spatula for dispensing beads

Select on the pull down menus below:

  • the model for use with snap cap tubes (standard) or screw cap tubes
  • standard or upgraded electronics and CE certification ($200 additional)
  • standard 2 year warranty or extended 4 year warranty with priority service ($293 additional)
  • basic starter kit (included, as described above) or a deluxe starter kit (described on the accessories tab)
 

BBY24M Bullet Blender Storm $3,450.00

BBY24M-Bullet-Blender-Storm

The BULLET BLENDER STORM is the most powerful member of the Bullet Blender family.  Homogenize up to 24 of your toughest samples (mouse femur, skin, cartilage, tumor, etc.) in just minutes.  Air cooling™ minimizes sample heat up. Uses 1.5ml eppendorf® safe-lock tubes.

Includes the following:

  • The BULLET BLENDER STORM
  • Operator's manual
  • 24V DC Wall plug power supply (UL/CE)
  • Basic starter kit which includes:
    • Bead Sample Pack BSP-MC contains 10mL each of eight different bead types.
    • Spatula for dispensing beads
 

BBX5MB Bullet Blender 5 Blue homogenizer $3,450.00

BBX5MB-Bullet-Blender-5-Blue-homogenizer

For use with 5 mL tubes, up to 12 at a time, equipped with Air Cooling™.

Includes the following:

  • The BULLET BLENDER® (with new improved housing!)
  • Operator's manual
  • 24V DC Wall plug power supply (UL/CE)
  • Basic starter kit which includes:
    • Bead Sample Pack BSP-5M contains 10mL each of seven different bead types.
    • Spatula for dispensing beads
 

BB50-DX Bullet Blender 50-DX homogenizer $3,955.00

BB50-DX-Bullet-Blender-50-DX-homogenizer

Extra-powerful Bullet Blender® 50-DX homogenizes better and faster. Processes up to 4 tough tissue samples or up to 8 soft samples in 50 mL tubes in parallel. Each tissue sample can be up to 3.5 g or cell culture combined with buffer up to 20 ml. Includes: BSP-50B bead sample pack which has samples (20 ml) of 7 types of beads, bead spoons, and a sample bag of 50 mL tubes.

Includes the following:

  • The BULLET BLENDER®
  • Operator's manual
  • 12V DC Wall plug power supply (UL/CE)
  • Basic starter kit which includes:
    • Bead Sample Pack BSP-50B contains 20mL centrifuge tubes of several different types of beads
    • Spoon for dispensing beads
 

BioBox enhancement for Bullet Blender homogenizer $3,300.00

BioBox-enhancement-for-Bullet-Blender-homogenizer

The Bullet Blender® high-throughput homogenizer with BioBox™ enhancement enables you to homogenize up to 24 samples - tissue, cells, etc. - simultaneously in separate screw-cap microcentrifuge tubes, with additional protection against pathogens and other potentially hazardous samples. Need to quickly process your samples? No problem! Grind up tissue, cells, small organisms, and more in just 3-5 minutes. Full automation ensures that you get highly reproducible results, while the locking enclosure, kept under negative pressure, provides an extra level of protection unmatched by other automated homogenization systems! Also, since your samples are contained inside the microcentrifuge tubes the entire time, the Bullet Blender with BioBox™ reduces the handling of dangerous samples. Simply load up to 300mg of your samples with grinding beads and your choice of buffer in standard screw-cap microcentrifuge tubes. Place the tubes into the Bullet Blender with BioBox™ (pictured above), close the Bullet Blender and the BioBox™ and lock the containment unit. The run is started using the exterior control panel and then our patented Striking Technology causes the beads to be rapidly agitated inside the tubes, breaking up the sample and lysing the cells in just a few minutes. Extract DNA, RNA, proteins, small molecules, or even intact organelles, bacteria, or viruses!

The BioBox™ enhancement for the Bullet Blender® offers an extra barrier of protection. The BioBox™ enhancement must be ordered with a BBX-screw cap microcentrifuge tube model Bullet Blender®. With this enhancement, the Bullet Blender® is built into a negative pressure, locking containment unit. The housing and containment unit are clear so leaks or spills are readily identifiable. Controls are mounted on the outside of the containment unit.

* This is a factory installed enhancement, so the BBX24W or BBX24BW must be ordered at the same time.

The BioBox™ and Bullet Blender® units ordered with the BioBox™ are final sale only.

 

FBBX Field Blender enhancement portable homogenizer $350.00

FBBX-Field-Blender-enhancement-portable-homogenizer

The Bullet Blenders® are a family of high quality homogenizers that enable high yields and consistent results. Applications include isolation of RNA, DNA, proteins, some organelles, and some single-celled organisms. The use of a simple, patented technology in this user friendly, high throughput homogenizer, enables great versatility, reliability, and high value.

The Field Blender upgrade, available with microtube model Bullet Blenders, allows you to homogenize samples on the go - no external power required!  Weighs only 9 pounds including the internal rechargeable battery and fits into most backpacks.  Padded handle.  Reduced 6-tube capacity.  Includes a vehicle charger for recharging the Field Blender on the road.  Must be purchased with a microcentrifuge tube Bullet Blender: BBX24, BBX24W, BBX24B, or BBX24BW.  Select from list below.  Only available for domestic sales.

 

EW-BBX Extended Warranty for BBX series Bullet Blender $316.00

The EW-BBX provides 4 years of worry free operation.  This extends the warranty for BBX model Bullet Blenders from two to four years, parts and labor, and gives you priority repair service.  Must be purchased when the Bullet Blender is purchased.  Please note that this does not cover Bullet Blenders purchased in conjunction with the BioBox (BIOX).

 
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