Bullet Blender, HOMOGENIZER of Cells and Tissue, lyse, disrupt, or homogenize cell cultures, vortex or mix, cell lysing, cell homogenization, tissue lysing, tissue homogenization, high throughput, homogenization, bead beater samples, beadbeater, bead beater, biospec, tissue lyser, tissuelyser, qiagen tissuelyser, ultrasonic disrupter, ultrasonic cell disruptor, cell disrupter

Next Advance Inc produces: the Freedom Rocker which automatically processes western, southern, and northern blots and gels; laboratory platform rockers; pressure injection cells; and more.

We specialize in Rockers, Pumps, Injectors, and Automated Blot Processors. Call 1.518.674.3510

Automated
Blot Processor
Capillary
Loader
Syringe Pumps Homogenizer
Cell Disrupter
Bullet Blender Family - The easiest and coolest way to lyse and homogenize tissue

Fast, Consistent Results

The BULLET BLENDER™ prepares up to 24 samples in just minutes. All of the samples are automatically homogenized the same, so there is very little variation from sample to sample. See the Protocols pages for preparation times and speeds.

No Cross Contamination

There are no probes or blades to cause cross contamination or sample loss. The sample tubes are kept closed during agitation, as the cells or tissue are disrupted. There are no probes to clean between samples.

Samples Stay Cool

The instrument uses very little power due to the unique, patented design, so there is very little heat build up in the instrument or inside the sample tubes. It uses a small DC motor to agitate the individual tubes, not ultrasonics. Also, because the motor does not need to agitate any heavy platforms or plates, it is small and will last for years.

Convenient, Ease of Use

Simply place your cells or tissue, and optionally some beads, in standard tubes, and load the tubes into the BULLET BLENDER™. Set the duration (typically several minutes) and speed (vigorousness). There are no probes to clean. It is much quieter than a sonicator and the samples stay cooler, too!

Risk Free

The BULLET BLENDERS™ come with a 30 day money back guarantee and a 2 year warranty. The simple, reliable design enables the BULLET BLENDERS™ to sell for one half to one fifth the price of ultrasonic or other agitation based instruments, yet provides an easier, quicker cooler technique.

The easiest and coolest way to lyse cells and homogenize tissue.



The BULLET BLENDER™ enables you to homogenize, disrupt, or lyse 24 tissue or cell culture samples at a time. Load the samples into polypropylene microcentrifuge tubes, then place them in the BULLET BLENDER™. The "bullets" in the instrument vigorously strike all the sample tubes while in operation. The Bullet Blender™ is now available with Air Cooling™ to preserve your sample quality!

Applications:

Lysing cells such as yeast and E. coli, or mamallian cell culture, to homogenizing tough tissues such as cartilage, tumors, heart, aorta, tail snips, muscle, uterus, and hair, as well as other organs such as liver, spleen, kidney, brain, lung, pharynx, stomach / intestine, lymph nodes, adipose, and skin from rodents, primates, or any animal. Other organisms like Drosophila, C. elegans, Apis mellifera, and Danio rerio, are amenable to Bullet Blender™ processing. You can also homognize plant tissue such as leaves, beans, nuts, berries, roots, sugar cane, etc. It's also used for extended vortexing or grinding, like chemical extractions or in applications such as phenol/chloroform extraction, blood processsing, and meconium metabolite extraction.

DNA RNA Protein
from plant samples from tail snips from E. coli samples

Use the Bullet Blender to homogenize plant leaves, stems, and more.

Genomic DNA samples in agarose gel stained with ethidium  bromide.


Lanes 1-4 = Tobacco leaf DNA

λ = λ phage Hind III digest

Lanes 5-8 = Rice leaf DNA samples

The Bullet Blender homogenizes tumors allowing the isolation of intact RNA.

Total RNA gel. RNA Integrity Number = 8.5

(thanks to Madhu Prasad @ U. Michigan)

Use the Bullet Blender to lyse or homogenize cell cultures.

 

SDS-PAGE gel

stained with Coomassie Blue
wc = whole cell

sf = soluble fraction

Left two lanes control

Right two lanes induced


Features:

  • Compact - The footprint is only 8in. (20cm) wide by 10in. (25cm) deep

  • High Throughput

      • The Bullet Blender™ and Bullet Blender™ BLUE : twenty-four 1.5mL to 2.0mL microcentrifuge tubes

      • Bullet Blender™ BLUE 50: nine 50mL polypropylene tubes.

  • Easy  - User friendly with only two settings to select: time and speed (up to 5 minutes for microcentrifuge tubes, up to 15 min. for 50 mL tubes.   Momentary on by pressing the "Start" button.

  • Versatile - Use the Bullet Blender in different laboratory environments, including cold rooms (4°C to 60°C, avoid condensing conditions).  Requires only an electrical outlet for operation.

  • CE certified 24V power supply, shipped with the proper plug configuration for your wall outlets.

  • CE certified instruments with upgraded electronics available.

  • Air Cooling™ on  "BLUE" models prevents the instrument from heating up when processing multiple rounds of samples.  The COOLEST homogenizer available!

  • Patented striking technology.

  • Built in the USA for years of trouble free use.

  • Warranty: two years parts and labor, three years on the motor.

  • 30-day money back guarantee.

 


chevron Fast, Consistent Results

The BULLET BLENDER™ prepares up to 24 samples in just minutes.  All of the samples are automatically homogenized the same, so there is very little variation from sample to sample.  See the Protocols pages for preparation times and speeds.

chevron No Cross-Contamination or Sample Loss

There are no probes or blades to cause cross contamination or sample loss.   The sample tubes are kept closed during agitation, as the cells or tissue are disrupted.  There are no probes to clean between samples.

 

chevron Samples Stay COOL

The instrument uses very little power due to the unique, patented design, so there is very little heat build up in the instrument or inside the sample tubes.  It uses a small DC motor to agitate the individual tubes, not ultrasonics.   Also, because the motor does not need to agitate any heavy platforms or plates, it is small and will last for years.

 

chevron Convenient to Use

Simply place your cells or tissue, and optionally some beads, in standard tubes, and load the tubes into the BULLET BLENDER™.   Set the duration (typically several minutes) and speed (vigorousness).  There are no probes to clean.  It is much quieter than a sonicator and the samples stay cooler, too!

 

chevron Risk Free Purchase

The BULLET BLENDERS™ come with a 30 day money back guarantee and a 2 year warranty. The simple, reliable design enables the BULLET BLENDERS™ to sell for one half to one fifth the price of ultrasonic or other agitation based instruments, yet provides an easier, quicker cooler technique.



The Bullet Blender™ Family

The BULLET BLENDER™ enables you to disrupt or homogenize many samples at a time, by incorporating patented striking technology.  The sample tubes are forcefully agitated thousands of times per minute, inducing vigorous motion of the substances inside the tubes.

Simply place your sample, some buffer, and optionally some beads in standard polypropylene tubes.  Place the tubes in the BULLET BLENDER™ and run for a few minutes. Afterwards, place the sample tubes in a centrifuge to separate the lysate. 

Because the samples are in separate tubes and no probes contact the samples, cross contamination is very easy to prevent. 

The patented design requires very little power, so the motor will last for years.  Also, the motor will not heat up significantly, so the samples stay cool.  The addition of beads in the sample tubes allows disruption or thorough  homogenization of cells and tissues.  Tune the extent of disruption by adjusting the

Air Cooling™ is an option on the microtube model and standard on the 5 mL and 50 mL tube model.  The Air Cooling™ entails fans which exchange air with their surroundings; they have nothing that actually chills the instrument.  Air Cooling™ is useful if you're running several sample cycles in a row or if your samples are extra sensitive to heating up.  Normally, the samples in the Bullet Blender™ only heat up a few degrees and stay quite cool.  However, if you're running a second batch of samples soon afterwards, they will heat up a little more because the Bullet Blender™ is starting out slightly warmer. The Air Cooling™ keeps the Bullet Blender™ cooler so that the first batch of samples heat up a little less and subsequent batches are kept just about as cool as the first batch.

NEW! - The Bullet Blender™ BLUE 5

The Bullet Blender™ BLUE 5 contains all the homogenizing power of the original Bullet Blender with over 3 times the capacity! Homogenize up to one gram of tough tissue, soft tissue, cell culture, or small organisms in 5ml screw-cap tubes - usually in under 5 minutes! Holds up to 12 tubes. Because the Bullet Blender™ BLUE 5, has a larger motor than the others, this version is only available with Air Cooling™.

The Bullet Blender™ BLUE 50

Similar to the original Bullet Blender™, this model holds up to 9 of 50 mL tubes at a time.  The sample, lysis buffer, and beads should occupy no more than 15 ml of any tube to allow plenty of room for the sample and beads to slosh around.  While this version is not suitable for tough tissue, it is ideal for larger volumes of cell culture and very soft tissue samples, such as adipose or brain.  This model utilizes BD Falcon or Krackeler brand polypropylene 50 ml tubes; tubes that are a slightly different size may not work properly.  Because of the somewhat longer processing times (about 3 times longer than with microcentrifuge tubes), all Bullet Blender 50s are equipped with Air Cooling™.

 

Click here to see sample protocols or answers to frequently asked questions (FAQs).


Still not sure if the Bullet Blender is right for you?
« Click here to request a demo! »

BBX24   BULLET BLENDER™ ........... $1,995  (plus shipping and taxes)

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For homogenizing, mixing or vortexing in microcentrifuge tubes (1.5 to 2.0 mL), up to 24 at a time.

 

Includes the following:

·   the BULLET BLENDER™ (with new improved housing!)

·   operator's manual

·   24V DC Wall plug power supply (UL/CE)

·   Bead Sample Pack BSP-MC — contains 10mL centrifuge tubes of eight different bead types.

·   spatula for dispensing beads



BBX24-CE   BULLET BLENDER™, CE certified model ........... $2,195  (plus shipping and taxes)
Similar to BBX24 Bullet Blender™, with upgraded electronics and CE certification.

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BBX24B   BULLET BLENDER™ BLUE ........... $2,295  (plus shipping and taxes)

                       Check Out Now

The BULLET BLENDER™BLUE improves upon the original Bullet Blender™ — the BLUE model has Air Cooling™ technology.   It keeps the samples from heating up when processing multiple rounds of samples. This unit is also for homogenizing, mixing or vortexing in microcentrifuge tubes (1.5 to 2.0 mL), up to 24 at a

 

Includes the following:

·   the BULLET BLENDER™ BLUE instrument (with new improved housing!)

·   operator's manual

·   24V DC Wall plug power supply (UL/CE)

·   Bead Sample Pack BSP-MC — eight different bead types in 10mL centrifuge tubes

·   spatula for dispensing beads



BBX24B-CE   BULLET BLENDER™ BLUE, CE certified model ........... $2,495  (plus shipping and taxes)
Similar to BBX24B Bullet Blender™ Blue, with upgraded electronics and CE certification.

                       Check Out Now



BBX5MB   BULLET BLENDER™ 5 BLUE ........... $2,695  (plus shipping and taxes)

                      Check Out Now

For use with 5 mL tubes, up to twelve at a time, equipped with Air Cooling™.

Includes the following:

·   BULLET BLENDER™ 5 BLUE instrument

·   operator's manual

·   24V DC Wall plug power supply (UL/CE)

·   Bead Sample Pack BSP-5M — contains 10mL centrifuge tubes of eight different bead types.



BBX5MB-CE   BULLET BLENDER™ 5 BLUE, CE certified model ........... Available Soon 
Similar to BBX5MB Bullet Blender™ 5 BLUE, with upgraded electronics and CE certification.

                       Check Out Now



BBX50B   BULLET BLENDER™ 50 BLUE  ........... $2,595  (plus shipping and taxes)

                       Check Out Now

For use with 50 mL tubes, up to nine at a time, equipped with Air Cooling™.

Includes the following:

·   BULLET BLENDER™ 50 BLUE instrument (with new improved housing!)

·   operator's manual

·   24V DC Wall plug power supply (UL/CE)

·   Bead Sample Pack BSP-50B— contains 20mL of seven different bead types.



BBX50B-CE   BULLET BLENDER™ 50 BLUE, CE certified model ........... $2,795  (plus shipping and taxes)
Similar to BBX50B Bullet Blender™ 50 BLUE, with upgraded electronics and CE certification.

                       Check Out Now


DELUXE STARTER KITS


DSK-1 Deluxe Starter Kit   .......... $265 (plus shipping and taxes)

The Deluxe Starter Kit 1 includes TUBE1EP5, 1 box of Eppendorf Safe-Lock tubes; 5 spatulas (a sub-pack of SPAT1); and BSP-ALL, a sample tube of each of the standard beads we sell (does not include the RNase-free beads). A $333 value.

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DSK-RNA2 Deluxe Starter Kit   .......... $415 (plus shipping and taxes.
The Deluxe Starter Kit for RNA work includes TUBE1EP5-S, 1 box of 500 sterile Eppendorf Safe-Lock tubes, PCR clean, Free of RNase and DNase; SPAT1, box of 50 individually packaged spatulas, RNase/DNase free, non-pyrogenic, antistatic, sterile; and RNase-free beads GB01-RNA, ZrOB05-RNA, ZrOB10-RNA, ZrOB20-RNA, SSB02-RNA, and SSB14B-RNA. A $498 value.

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EXTENDED WARRANTY

EW-BBX   Extended Warranty for BBX or CDX series Bullet Blender   .......... $250
The EW-BBX extends the Bullet Blender warranty from two to four years and gives you priority on repairs. Must be purchased when the Bullet Blender is purchased.

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