Ideal for Tumor Tissue Homogenization

Do you spend lots of time and effort homogenizing tumor tissue samples? The Bullet Blender® is a multi-sample homogenizer that delivers superior results. No other homogenizer comes close to delivering the Bullet Blender’s winning combination of top-quality performance and budget-friendly affordability.

The Bullet Blender® Homogenizer
Save Time, Effort and Get Superior Results

  • Consistent and High Yield Results Run up to 24 samples at the same time under microprocessor-controlled conditions, ensuring experimental reproducibility and high yield. Process samples from 10mg or less up to 3.5g.
  • No Cross Contamination No part of the Bullet Blender® ever touches the tumor tissue samples – the sample tubes are kept closed during homogenization. There are no probes to clean between samples.
  • Samples Stay Cool Homogenizing causes only a few degrees of heating. Our “Blue” model comes with a fan to maintain ambient temperatures.
  • Easy and Convenient to Use Just place beads and buffer along with your tumor tissue sample in standard tubes, load tubes directly in the Bullet Blender, select time and speed, and press start.
  • Risk Free Purchase The Bullet Blender® comes with a 30 day money back guarantee and a 2 year warranty, with a 3 year warranty on the motor. The simple, reliable design enables the Bullet Blenders to sell for a fraction of the price of ultrasonic or other agitation based instruments, yet provides an easier, quicker technique.
Bullet Blender Homogenizer

Selected Publications for Tumor Tissue

Masterson, L., Winder, D. M., Ball, S. L. R., Vaughan, K., Lehmann, M., Scholtz, L.-U., … Goon, P. K. C. (2016). Molecular analyses of unselected head and neck cancer cases demonstrates that human papillomavirus transcriptional activity is positively associated with survival and prognosis. BMC Cancer, 16, 367.
Yoshida, Y., Ozawa, T., Yao, T.-W., Shen, W., Brown, D., Parsa, A. T., … James, C. D. (2014). NT113, a Pan-ERBB Inhibitor with High Brain Penetrance, Inhibits the Growth of Glioblastoma Xenografts with EGFR Amplification. Molecular Cancer Therapeutics, 13(12), 2919–2929.
Valentino, J. D., Li, J., Zaytseva, Y. Y., Mustain, W. C., Elliott, V. A., Kim, J. T., … Evers, B. M. (2014). Cotargeting the PI3K and RAS Pathways for the Treatment of Neuroendocrine Tumors. Clinical Cancer Research, 20(5), 1212–1222.
Jallouk, A. P., Palekar, R. U., Marsh, J. N., Pan, H., Pham, C. T. N., Schlesinger, P. H., & Wickline, S. A. (2015). Delivery of a Protease-Activated Cytolytic Peptide Prodrug by Perfluorocarbon Nanoparticles. Bioconjugate Chemistry, 26(8), 1640–1650.
Keung, E. Z., Akdemir, K. C., Al Sannaa, G. A., Garnett, J., Lev, D., Torres, K. E., … Chin, L. (2015). Increased H3K9me3 drives dedifferentiated phenotype via KLF6 repression in liposarcoma. Journal of Clinical Investigation, 125(8), 2965–2978.
Adelaiye, R., Ciamporcero, E., Miles, K. M., Sotomayor, P., Bard, J., Tsompana, M., … Pili, R. (2015). Sunitinib Dose Escalation Overcomes Transient Resistance in Clear Cell Renal Cell Carcinoma and Is Associated with Epigenetic Modifications. Molecular Cancer Therapeutics, 14(2), 513–522.
Allensworth, J. L., Evans, M. K., Bertucci, F., Aldrich, A. J., Festa, R. A., Finetti, P., … Devi, G. R. (2015). Disulfiram (DSF) acts as a copper ionophore to induce copper-dependent oxidative stress and mediate anti-tumor efficacy in inflammatory breast cancer. Molecular Oncology, 9(6), 1155–1168.
Pilon, J. L., Clausen, D. J., Hansen, R. J., Lunghofer, P. J., Charles, B., Rose, B. J., … Williams, R. M. (2015). Comparative pharmacokinetic properties and antitumor activity of the marine HDACi Largazole and Largazole peptide isostere. Cancer Chemotherapy and Pharmacology, 75(4), 671–682.
Ruhaak, L. R., Taylor, S. L., Stroble, C., Nguyen, U. T., Parker, E. A., Song, T., … Miyamoto, S. (2015). Differential N-Glycosylation Patterns in Lung Adenocarcinoma Tissue. Journal of Proteome Research, 14(11), 4538–4549.
Byun, S., Shin, S. H., Lee, E., Lee, J., Lee, S.-Y., Farrand, L., … Dong, Z. (2015). The retinoic acid derivative, ABPN, inhibits pancreatic cancer through induction of Nrdp1. Carcinogenesis, bgv148.
Danan-Gotthold, M., Golan-Gerstl, R., Eisenberg, E., Meir, K., Karni, R., & Levanon, E. Y. (2015). Identification of recurrent regulated alternative splicing events across human solid tumors. Nucleic Acids Research, 43(10), 5130–5144.
Makowski, L., Zhou, C., Zhong, Y., Kuan, P. F., Fan, C., Sampey, B. P., … Bae-Jump, V. L. (2014). Obesity increases tumor aggressiveness in a genetically engineered mouse model of serous ovarian cancer. Gynecologic Oncology, 133(1), 90–97.
Awasthi, N., Hinz, S., Brekken, R. A., Schwarz, M. A., & Schwarz, R. E. (2015). Nintedanib, a triple angiokinase inhibitor, enhances cytotoxic therapy response in pancreatic cancer. Cancer Letters, 358(1), 59–66.
Ramos, P., Karnezis, A. N., Craig, D. W., Sekulic, A., Russell, M. L., Hendricks, W. P. D., … Trent, J. M. (2014). Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4. Nature Genetics, 46(5), 427–429.
Marien, E., Meister, M., Muley, T., Fieuws, S., Bordel, S., Derua, R., … Swinnen, J. V. (2015). Non-small cell lung cancer is characterized by dramatic changes in phospholipid profiles: Altered Phospholipid Profiles in NSCLC. International Journal of Cancer, 137(7), 1539–1548.
León-Cabrera, S., Callejas, B. E., Ledesma-Soto, Y., Coronel, J., Pérez-Plasencia, C., Gutiérrez-Cirlos, E. B., … Terrazas, L. I. (2014). Extraintestinal Helminth Infection Reduces the Development of Colitis-Associated Tumorigenesis. International Journal of Biological Sciences, 10(9), 948–956.
Grasso, C. S., Tang, Y., Truffaux, N., Berlow, N. E., Liu, L., Debily, M.-A., … Monje, M. (2015). Functionally defined therapeutic targets in diffuse intrinsic pontine glioma. Nature Medicine, 21(6), 555–559.
Naba, A., Clauser, K. R., Whittaker, C. A., Carr, S. A., Tanabe, K. K., & Hynes, R. O. (2014). Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver. BMC Cancer, 14(1), 518.
Shanmugam, V., Ramanathan, R. K., Lavender, N. A., Sinari, S., Chadha, M., Liang, W. S., … Carpten, J. D. (2014). Whole genome sequencing reveals potential targets for therapy in patients with refractory KRAS mutated metastatic colorectal cancer. BMC Medical Genomics, 7(1), 36.
Dao, V., Pandeswara, S., Liu, Y., Hurez, V., Dodds, S., Callaway, D., … Curiel, T. J. (2015). Prevention of Carcinogen and Inflammation-Induced Dermal Cancer by Oral Rapamycin Includes Reducing Genetic Damage. Cancer Prevention Research, 8(5), 400–409.
Scrimieri, F., Askew, D., Corn, D. J., Eid, S., Bobanga, I. D., Bjelac, J. A., … Huang, A. Y. (2013). Murine leukemia virus envelope gp70 is a shared biomarker for the high-sensitivity quantification of murine tumor burden. OncoImmunology, 2(11), e26889.
Sahu, R. P., Turner, M. J., DaSilva, S. C., Rashid, B. M., Ocana, J. A., Perkins, S. M., … Travers, J. B. (2012). The environmental stressor ultraviolet B radiation inhibits murine antitumor immunity through its ability to generate platelet-activating factor agonists. Carcinogenesis, 33(7), 1360–1367.
Goh, J., Tsai, J., Bammler, T. K., Farin, F. M., Endicott, E., & Ladiges, W. C. (2013). Exercise Training in Transgenic Mice Is Associated with Attenuation of Early Breast Cancer Growth in a Dose-Dependent Manner. PLoS ONE, 8(11), e80123.
Travica, S., Pors, K., Loadman, P. M., Shnyder, S. D., Johansson, I., Alandas, M. N., … Ingelman-Sundberg, M. (2013). Colon Cancer-Specific Cytochrome P450 2W1 Converts Duocarmycin Analogues into Potent Tumor Cytotoxins. Clinical Cancer Research, 19(11), 2952–2961.
Liang, W. S., Aldrich, J., Tembe, W., Kurdoglu, A., Cherni, I., Phillips, L., … Craig, D. W. (2014). Long insert whole genome sequencing for copy number variant and translocation detection. Nucleic Acids Research, 42(2), e8–e8.
Liang, W. S., Craig, D. W., Carpten, J., Borad, M. J., Demeure, M. J., Weiss, G. J., … Von Hoff, D. (2012). Genome-Wide Characterization of Pancreatic Adenocarcinoma Patients Using Next Generation Sequencing. PLoS ONE, 7(10), e43192.
Weiss, G. J., Liang, W. S., Izatt, T., Arora, S., Cherni, I., Raju, R. N., … Carpten, J. D. (2012). Paired Tumor and Normal Whole Genome Sequencing of Metastatic Olfactory Neuroblastoma. PLoS ONE, 7(5), e37029.
Poulikakos, P. I., Persaud, Y., Janakiraman, M., Kong, X., Ng, C., Moriceau, G., … Solit, D. B. (2011). RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E). Nature, 480(7377), 387–390.
Gilbreath, J. J., Semino-Mora, C., Friedline, C. J., Liu, H., Bodi, K. L., McAvoy, T. J., … Merrell, D. (2013). A core microbiome associated with the peritoneal tumors of pseudomyxoma peritonei. Orphanet Journal of Rare Diseases, 8(1), 105.
Winder, D. M., Ball, S. L., Vaughan, K., Hanna, N., Woo, Y., Fränzer, J.-T., … Goon, P. K. (2009). Sensitive HPV detection in oropharyngeal cancers. BMC Cancer, 9(1), 440.
Nagarkar, D. R., Poposki, J. A., Tan, B. K., Comeau, M. R., Peters, A. T., Hulse, K. E., … Kato, A. (2013). Thymic stromal lymphopoietin activity is increased in nasal polyps of patients with chronic rhinosinusitis. Journal of Allergy and Clinical Immunology, 132(3), 593-600.e12.
Ke, H., Augustine, C. K., Gandham, V. D., Jin, J. Y., Tyler, D. S., Akiyama, S. K., … Zhang, J. Y. (2013). CYLD Inhibits Melanoma Growth and Progression through Suppression of the JNK/AP-1 and β1-Integrin Signaling Pathways. Journal of Investigative Dermatology, 133(1), 221–229.
To learn more about the Bullet Blender, click here.
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