Bullet Blender®

Overview

The easiest and coolest way to lyse cells and homogenize tissue.



Bullet Blender homogenization, before and after pics

The Bullet Blender® enables you to homogenize, disrupt, or lyse up to 24 tissue or cell culture samples at a time. Load the samples into standard polypropylene tubes, then place them in the BULLET BLENDER. The "bullets" in the instrument vigorously strike all of the tubes and homogenize your sample in minutes. The Bullet Blender homogenizer Gold model family has 4°C Cooling™!

Why choose the Bullet Blender?

Consistent and High Yield Results

The BULLET BLENDER homogenizer prepares up to 24 samples in just minutes. All of the samples are automatically homogenized in the same manner, with high yields, so there is very little variation from sample to sample. See the Protocols tab for preparation times and speeds.

No Cross-Contamination or Sample Loss

There are no probes or blades to cause cross contamination or sample loss, which also means there are no parts to clean between runs. The sample tubes are kept closed and self-contained during homogenization.

Samples Stay COOL

No cool down required. The Bullet Blender homogenizers use very little power due to the unique, patented design. There is very little heating of the samples because the sample tubes vibrate vigorously in air, keeping them cool, rather than being subjected to frictional heating as the tubes rub against the walls of a holder. Also, because the motor does not need to agitate any heavy platforms or plates, it is small and will last for many years.
Learn more about cooling in the Bullet Blender!

So Easy To Use

Simply place your sample, beads and buffer in standard tubes, and load the tubes into the BULLET BLENDER homogenizer. Tune the extent of disruption by adjusting the run time and speed. Afterwards, place the sample tubes in a centrifuge to separate the lysate. No special holders are needed. There are no clamp plates nor locking rings to fiddle with.

Risk Free Purchase

BULLET BLENDER homogenizers come with a 30 day money back guarantee and a 2 year warranty (an extended, 4-year warranty is available). The simple, reliable design enables the BULLET BLENDER to sell for one half the price of other agitation based instruments, yet provides an easier, quicker, cooler technique.

Features

Bullet Blender® Gold Models with 4°C Cooling

Bullet Blender Gold for Tissue Disruption Homogenization

The Bullet Blender Gold model Bullet Blender combines dry ice cooling to keep samples at 4°C, noise insulation to keep homogenization quiet, and extra-powerful homogenization to give you the excellent results. No other homogenizer comes close to delivering the Bullet Blender’s winning combination of top quality performance, superior results and budget-friendly affordability.

Features in Gold Models

  • AGITATION: Vigorous agitation at a range of frequencies and in multiple directions, for thorough homogenization of even the toughest samples.
  • CAPACITY: Process up to 24 samples in 1.5 mL tubes, 12 samples in 5 mL tubes, or up to 8 samples in 50 mL tubes.
  • COOLING: Dry ice cooling system keeps samples at 4°C, within a few degrees. Sample tube oscillation in open air ensures good convective cooling.
  • QUIET: Sound insulation keeps homogenization quiet.
  • EASY TO USE:Just set the speed and time and press start.
  • SPEED CONTROL: Adjustable to handle gentle vortexing to homogenization of bones.
  • WORLDWIDE: Power supply can be used anywhere worldwide.
  • CE Certified: CE Certified models available.
  • RISK FREE: 2 year warranty and 30 day money-back guarantee.
  • MADE IN THE USA.

Features in all Models

  • AGITATION: Vigorous agitation at a range of frequencies and in multiple directions, for thorough homogenization of even the toughest samples.
  • CAPACITY: Process up to 24 samples in 1.5 mL tubes, 12 samples in 5 mL tubes, or up to 8 samples in 50 mL tubes.
  • COOLING: Air Cooling™ (all models except the basic Bullet Blender) reduces heating up of samples with ambient air. Sample tube oscillation in open air ensures good convective cooling.
  • EASY TO USE: Just set the speed and time and press start.
  • SPEED CONTROL: Adjustable to handle gentle vortexing to homogenization of bones.
  • WORLDWIDE: Power supply can be used anywhere worldwide.
  • CE Certified: CE Certified models available.
  • RISK FREE: 2 year warranty and 30 day money-back guarantee.
  • MADE IN THE USA

Models

There are several Bullet Blender models for different purposes and different size samples, using microcentrifuge tubes (0 – 300 uL samples), 5 mL tubes (100 – 1 mL samples), and 50 mL tubes (100 – 3.5 mL samples).

The microcentrifuge tubes models include:
  • the basic Bullet Blender, a lower power model with the lowest cost and works only with snap cap tubes
  • the Bullet Blender Blue which has Air Cooling™ which forces ambient air past the samples to keep them cooler and also works with only snap cap tubes.
  • the Bullet Blender Storm, the most popular model, because it has a more powerful motor that can handle the toughest samples and Air Cooling, which forces ambient air past your samples. The Storm model works with snap cap and our RINO® screw cap tubes, made from an extra tough material.
  • the Bullet Blender Gold, the best model for working with RNA because it has the powerful motor found in the Storm model, works with snap cap and our RINO screw cap tubes, and incorporates dry ice 4C Cooling™ to keep your samples at 4C. Using a temperature sensor in the instrument, monitoring the motor and using an algorithm, a fan is modulated to blow the right amount of air past dry ice and then mixed with ambient air in the instrument and past your samples to keep them near 4C.
  • the Bullet Blender Gold Plus, similar to the Gold, with a color graphics user control screen. This model has an updatable library of protocols with color photographs and a user guide with instructions for preparing samples.

Bullet Blender Models: Microcentrifuge Tubes

(samples 0-300 µl)

Feature Bullet Blender homogenizer
High Throughput- Homogenizes up to 24 samples at a time
Range of speeds allows for gentle vortexing, vigorous homogenization, or anything in between
Can be used in temperatures ranging from 4°C to 40°C*
With 4°C Cooling™
With Air Cooling to keep the inside of the instrument near ambient temperature
Can homogenize samples in RINO® screw-cap tubes
Can homogenize samples in Eppendorf® Safe-lock™ snap-cap
Extra-powerful homogenization for tough samples
Made in the USA

 

The 5 mL tube models work with samples from 100 uL – 1 mL, or 100 mg to 1 g. They include:

  • the Bullet Blender 5 Storm, ideal for dry grinding of seeds and grains
  • the Bullet Blender 5E, which has Air Cooling™ and works well on most types of samples
  • the Bullet Blender 5 Gold, which is similar to the 5E, and has 4C cooling.

The 50 mL tubes models work with samples from 100 uL – 3.5 mL, or 100 mg to 3.g g. They include:

  • the Bullet Blender 50 DX, the lowest cost model for these larger samples
  • the Bullet Blender 50 Gold, which has 4C cooling.

Bullet Blender Models: Larger Samples in 5 and 50 mL Tubes

(samples over 300 µl)

Feature
Homogenization of up to 12 samples from 100 mg – 1 g (100 µl – 1 mL for plant tissue, insects and cell culture) in 5 mL Eppendorf® tubes
Homogenization of up to 12 samples from 100 mg – 1 g (100 µl – 1 mL for plant tissue, insects and cell culture), for wet or dry grinding in 5 mL Axygen® tubes
Homogenization of up to 8 samples from 100 mg – 3.5 g (100 µl – 3.5 mL for plant tissue, insects and cell culture) in 50 mL tubes
Range of speeds allows for gentle vortexing, vigorous homogenization, or anything in between
Can be used in temperatures ranging from 4°C to 40°C*
With Air Cooling to keep the inside of the instrument near ambient temperature
With 4°C Cooling™
Made in the USA

*avoid condensation, which will damage electronics and void the warranty.

Specifications:

  • Size: All BBX and BBY models are 9 in. (23 cm) wide by 11 in. (28 cm) deep by 8.5 in. (21.5 cm) high The BB50-DX model is 15 in. (38 cm) wide by 14 in. (35 cm) deep by 15 in. (38 cm) high The BB24-AU and BB50-AU models are 18 in. (46 cm) wide by 14 in. (35 cm) deep by 15 in (38 cm) high.
  • Weight: 8.5 to 33 lbs (4 to 15 kg), depending upon model
  • Run Times: UP to 5 minutes (15 minutes for the 50-DX and 50-AU). The Bullet Blender will automatically stop after the selected time is up.
  • Power Requirements: BBX24 and BBX24B models: 24 VDC, 0.75 Amp BBY24M and BBX5MB models: 24 VDC,2.5 Amp BB24-AU, BB25-AU and BB50-DX: 100-240 V, 2.5-4.5 A Plug configurations for international wall outlets available
  • Operating Temperature: 4 – 40°C
  • Relative Humidity: 5 – 90% non-condensing
  • CE certified instruments with upgraded configuration available
  • 30 day money back guarantee
  • 2 year warranty (extended warranties available)

Extended Warranties

Applications

homogenize forza2 Nucleotide RNA and DNA extraction using the Bullet Blender Tissue Homogenizer Viral extraction using the Bullet Blender Tissue Homogenizer Protein extraction using the Bullet Blender Tissue Homogenizer Organelle extraction using the Bullet Blender Tissue Homogenizer Nuclei Mitochondria Chemical extraction for analysis using the Bullet Blender Tissue Homogenizer lipids drugs toxins small molecules Bacterial isolation using the Bullet Blender Tissue Homogenizer Colony Forming Units Lymphocyte isolation using the Bullet Blender Tissue Homogenizer Generating Single Cell Suspensions using the Bullet Blender Tissue Homogenizer Nanoparticle generation for drug delivery liposomes Bullet Blender tissue homogenizer Extraction biofuel lipids from algae Bullet Blender homogenizer

What can you homogenize in a Bullet Blender?

Homogenize Tissue

Adipose, Adrenal Gland, Aorta, Bladder, Blood Vessel, Bone (small), Brain, Cartilage, Cecum, Colon, Cranium, Diaphragm, Duodenum, Ear, Epithelium, Eye, Feces, Fish Organs, Gallbladder, Genital Warts, Heart, Hypothalamus, Intestinal Mucosa, Intestine, Jaw, Jejunum, Kidney, Larynx, Liver, Lung, Lymph Node, Marrow, Meconium, Mouse Femur, and Tibia, Muscle, Nasal Tissue, Olfactory Mucosa, Oropharynx, Pancreas, Peritoneal Macrophages, Pharynx, Pituitary Gland, Placenta, Polyp, Salivary Gland, Skin, Spleen, Stomach, Tail Snips, Teeth, Testes, Thalamus, Thymus Gland, Thyroid Gland, Tongue, Trachea, Tumor, Umbilical Cord, Uterus, Wound Tissue

Lyse Cells

Bacteria,C. albicans, E. coli, Mammalian cell culture, S. cerevisiae, Stem Cells, Yeast

Homogenize Plant Material and Fungi

A thaliana, Algae, Beans, Blueberry, Corn, Flower Petals, Fungi, Ginger Rhizome, Horseradish Root, Leaves, Leek, Malanga (Tuber), Microsporidia, Moss, Mycelia, N. benthamiana, Nuts, Pine Needles, Pine Nut, Potato, Roots, Seeds, Sugar Cane Pulp, Tobacco, Tuber, Soy Bean Plant

Homogenize Small Organisms

Caterpillar, Crayfish, Crickets, Fruit Fly (Drosophila), Honeybee, Hookworm, Mosquito, Nematode (B. xylophilus), Plankton, Roundworm (C. elegans), Shrimp, Ticks, Zebrafish(D. rerio), Zooplankton

Dry Grind Samples

Dried soybeans, mung beans, corn, rice, surghum, cloves, barley, spelt, sunflower seeds, wheat berries, chickpeas and many more!

Samples stay cool in the Bullet Blender®.

Use the Bullet Blender for Forensic Applications

Results

 

Bullet Blender homogenizer and disrupter for tissue and cell cultures Bullet Blender for cell lysis tissue disruption Using the Bullet Blender homogernizer to create single cell suspensions Isolating bacterial with the Bullet Blender Checmial analysis and drug testing using the Bullet Blender

Beads & Accessories

Shop By Supplies

 

Shop By Bullet Blender Model

 

Dry Grinding Accessories

Publications

Use the tables below to find publications in which researchers used the Bullet Blender® to prepare their samples.

 

 

 

Other Applications (Publications coming soon…)
Biofuel Extraction from Algae Nanoparticle Generation (~100nm particles)
Generating Single Cell Suspensions for Re-inoculation Stem Cell Isolation from Adipose

 

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