Tissue Homogenizer & Homogenization Protocol

Ideal for Tissue Samples

Save Time, Effort and Get Superior Results with

The Bullet Blender® Homogenizer

  • Consistent Results
  • Samples Stay Cool
  • No Cross Contamination
  • Easy & Convenient
  • Risk Free

Do you spend lots of time and effort homogenizing tissue samples? The Bullet Blender® is a multi-sample homogenizer that delivers high quality and superior yields. No other homogenizer comes close to delivering the Bullet Blender’s winning combination of top-quality performance and budget-friendly affordability.

Consistent and High Yield Results

Run up to 24 samples at the same time under microprocessor-controlled conditions, ensuring experimental reproducibility and high yield. Process samples from 10mg or less up to 3.5g.

No Cross Contamination

No part of the Bullet Blender® ever touches the tissue – the sample tubes are kept closed during homogenization. There are no probes to clean between samples.

Samples Stay Cool

Homogenizing causes only a few degrees of heating. Our Gold models keep samples at 4°C.

Easy and Convenient to Use

Just place beads and buffer along with your tissue sample in standard tubes, load tubes directly in the Bullet Blender, select time and speed, and press start.

Risk Free Purchase

The Bullet Blender® comes with a 30 day money back guarantee and a 2 year warranty, with a 3 year warranty on the motor. The simple, reliable design enables the Bullet Blenders to sell for a fraction of the price of ultrasonic or other agitation based instruments, yet provides an easier, quicker technique.

Example Bullet Blender settings for Tissue Homogenization

Sample size

See the Protocol

microcentrifuge tube model (up to 300 mg) Small adipose tissue samples
5mL tube model (100mg - 1g) Medium adipose tissue samples
50mL tube model (100mg - 3.5g) Large adipose tissue samples
the Bullet Blender high-throughput tissue homogenizer
Three tubes with unhomogenized mouse femur.
Mouse Femur (Before)
Three tubes with homogenized mouse femur.
Mouse Femur Homogenized in the Bullet Blender

What can you homogenize in a Bullet Blender?

Adipose, Adrenal Gland, Aorta, Bladder, Blood Vessel, Bone, Brain, Cartilage, Cecum, Colon, Cranium, Diaphragm, Duodenum, Ear Punch, Eye, Feces, Fish Organs, Gallbladder, Genital Warts, Heart, Hypothalamus, Intestinal Mucosa, Intestine, Jejunum, Kidney, Larynx, Liver, Lung, Lymph Node, Marrow, Meconium, Mouse Femur and Tibia, Muscle, Nasal/Olfactory Mucosa, Oropharynx, Pancreas, Pharynx, Pituitary Gland, Placenta, Polyp, Salivary Gland, Skin, Spleen, Stomach, Tail Snips, Teeth, Testes, Thalamus, Thymus, Thyroid, Tongue, Trachea, Tumor, Umbilical Cord, Uterus

Don’t see your tissue? Want more guidance? Contact our application support scientists:



    Scientist using a Bullet Blender Gold

    Bullet Blender Models

    Selected publications for Tissue Homogenization​

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    Have any questions? Ask us!​